Today, I’ll select “literally,” as in “That was so funny, I literally peed my pants.” Trust me, the number of people who need to change clothes is not the same as the number of people who say that.
My second choice is “at the end of the day,” even though it’s in the question itself. It’s just so overused in so many contexts and not very effective in the first place.
But seriously, I could probably post a feature in my LJ where I select a cringeworthy buzzword or phrase every day, and not run out of subjects. I might run out of interested readers, though.